Broader Impacts

Supplemental Funding Opportunity: INTERN

Attention, Principle Investigators and graduate students! DCL 18-102 provides up to $55,000 per student in funding for up to six months to allow recipients to participate in research-based internships in STEM or STEM education research fields in non-academic settings.* The goal is to enable students to gain knowledge, skills, and experiences that prepare them for entry into non-academic careers. This opportunity is open to PIs who are supporting graduate students through any active NSF award. To be eligible, a graduate student must have completed at least one academic year in their graduate (master's or doctoral) program and be making satisfactory progress towards degree completion. For a description of the activities supported, visit the announcement page, then contact your program officer to discuss your proposal. *Principle investigators who currently hold an active award from MCB may also apply directly to MCB with a supplemental funding request.

Attention, Principal Investigators and graduate students! DCL 18-102 provides up to $55,000 per student in funding for up to six months to allow recipients to participate in research-based internships in STEM or STEM education research fields in non-academic settings.* The goal is to enable students to gain knowledge, skills, and experiences that prepare them for entry into non-academic careers.

This opportunity is open to PIs who are supporting graduate students through any active NSF award. To be eligible, a graduate student must have completed at least one academic year in their graduate (master’s or doctoral) program and be making satisfactory progress towards degree completion.

For a description of the activities supported, visit the announcement page, then contact your program officer to discuss your proposal.

*Principal investigators who currently hold an active award from MCB may also apply directly to MCB with a supplemental funding request.

Congratulations to the winners of the 2018 Nobel Prize in chemistry

Congratulations to MCB funded-researcher Dr. Frances Arnold, recipient of the 2018 Noble Prize in chemistry. Dr. Arnold is honored for her role in developing the field of directed evolution. As a researcher at California Institute of Technology, Dr. Arnold based her work on the principles of evolution to improve enzyme function; she used error prone polymerase chain reaction (PCR) to introduce random mutations in a gene of interest, introduced those genes into an E. coli library, allowed the mutants to compete, and selected for mutants that improved function. Enzymes optimized through this process can improve results anywhere enzymes are used such as: medicine, biotechnology, biofuels, research, industrial production, and home cleaning and processing applications.

“Dr. Arnold transformed the field of protein engineering and did so at a time when there were very few women in the field.  She combatted gender bias in academia by excelling and demonstrating to those of us who followed her that it was possible,” observed Theresa Good, Deputy Division Director of MCB. Dr. Arnold’s award brings the total number of female awardees in chemistry to five of 180 recipients, representing 2.8 percent of awards in chemistry; the percent of all Nobel Prizes awarded to women is slightly less than six percent.

This year’s award is shared with Dr. George P. Smith, University of Missouri, and Dr. Gregory Winter, Medical Research Council Laboratory of Molecular Biology, Cambridge, UK, for their work on phage display. Click on the link to read the Statement on the Nobel Prize in Chemistry by NSF Director Dr. Frances Córdova.

what’s your big idea?

What is it?   The NSF 2026 Idea Machine competition is an unprecedented opportunity to promote a new area of research that is important and exciting but not currently addressed by NSF. Ideas submitted will help set the stage for breakthrough research in science, technology, engineering, and mathematics (STEM) and STEM education through the nation’s 250th anniversary in 2026 and beyond.

How do I enter?   Submit your entry at the NSF 2026 Idea Machine website by October 26th, 2018.

Who’s eligible–and not eligible–to submit ideas?   All contestants must be either U.S. citizens, or permanent residents or legally reside in the U.S., and be over 14 years old on September 1, 2018. More details are available on the Eligibility & Rules page.

 

Better Communication, Better Science

Alexandre and Barnajeet
Dr. Gladys Alexandre, left, and REU participant Reena Barnajeet.

In 2015, researcher Dr. Gladys Alexandre learned something valuable: the addition of Reena Barnajeet, a hard of hearing student, to her lab improved the communication skills of everyone in the group. (more…)

“YOU SHOULD ALWAYS HAVE A HOBBY”

 

Broader Impacts* are just as important as Intellectual Merit in the NSF Merit Review process. Dr. Ahna Skop has found a recipe for broader impacts that’s given the public a taste for science. Learn the story of her not-so-secret ingredients.

Dr. Ahna SkopFor Dr. Ahna Skop, the key ingredients in the recipe for good broader impacts are found in a researcher’s personal passions. (more…)

RUI AWARD SUPPORTS 2017 STUDENT RESEARCH ACHIEVEMENT AWARDEE, RIMA REBIAI

Rima Rebia, Student Research Acheivement Award, Biophysical Society, Feb. 2017

Rima Rebiai, winner of the Biophysical Society’s “Student Research Achievement Award” stands next to her entry.

At the 61st Biophysical Society meeting held in New Orleans February 11-15, 2017, undergraduate researcher Rima Rebiai received the prestigious Student Research Achievement Award. Of the 14 awards made, Rebiai’s research was the only project focusing on nanoscale biophysics.

Rebiai’s research was funded in part by a Research in Undergraduate Institutions (RUI) grant from the Division of Molecular and Cellular Biosciences (MCB). RUI proposals support faculty at predominately undergraduate institutions to conduct research that builds institutional capacity for research and supports the integration of research and undergraduate education.

The research was a collaboration between and Dr. Emina Stojkovic, Bernard J. Brommel Research Professor, Department of Biology at Northeastern Illinois University, and Drs. Ken Nicholson and Stefan Tsonchev, Associate Professors in the Department of Chemistry. The award (#1413360) was the first to be awarded to the Biology Department in NEIU’s history, said Stojkovic. An interesting side note, Stojkovic added, is that she attended a similar meeting of the Biophysical Society as an undergraduate student 17 years ago with her research advisor, Dr. Anne Walter from St. Olaf College.

The university featured the honor on its News and Announcements page. According to Northeastern, Rebiai’s project, titled “Light-Induced Conformational Changes of S. aurantiaca Bacteriophytochromes as Revealed by Atomic Force Microscopy,” is the first to use atomic force microscopy to build structural characterization of light-regulated enzymes. Highlighting Stojkovic’s pride in Rebiai’s achievement, the article concludes with a quote: “This is a true honor to have our student stand on the national stage.” Rebiai is currently in her first year of Ph.D. studies at the University of Illinois-Chicago.

NATIONAL ALLIANCE FOR BROADER IMPACTS: THE POWER OF PARTNERSHIPS

NABI

In April, the National Alliance for Broader Impacts (NABI) held its fifth annual Broader Impacts Summit at Skamania Lodge in Stevenson, WA. NABI is a network of more than 600 individuals working together to build institutional capacity, advance broader impacts, and demonstrate the societal benefits of research. NABI members come from educational institutions, museums, science centers, zoos, botanical gardens, professional societies, private industry, foundations, and other organizations. A list of member institutions is available on the NABI website and you can read about the objectives of NABI in a prior post on the MCB Blog. Established in part with funding provided by the Division of Molecular and Cellular Biosciences, NABI events and resources help researchers create and develop impactful broader impacts activities.

At the summit, Dr. Suzanne Iacono, Head of the Office of Integrative Activities (OIA) at the National Science Foundation, delivered a keynote address entitled Broader Impacts at NSF. She noted, across proposals, student education and broadening participation were two main focus areas. These areas were also a major point of discussion in several of the sessions at the meeting.

The theme of the three-day summit was the “Power of Partnerships.” Sessions focused on three strands: innovative BI approaches and activities, faculty and student development and training, and broader impacts infrastructure, skills, and tools. Research into the role of partnerships in empowering high-quality outreach, models for public engagement partnerships, and best practices in the assessment and evaluation of broader impacts were presented, which created a foundation for data-driven conversations about broader impacts for the 21st century and beyond.  Presenters discussed how to construct strong science education and build outreach partnerships with a diverse array of partners such as citizen scientists, startup companies, museums, community partners, STEM graduate students, engineers, and faculty. Summit participants also learned how to use crowdfunding, cinema, social media, and Twitter as tools to facilitate outreach.  Discussion also focused on how to reach non-traditional public audiences, minorities underrepresented in STEM fields, and the next generation of scientists. Panelists offered lessons learned while establishing outreach partnerships such as University of Wisconsin – Madison Science Alliance, which connect scientists with K-12 educators, parents, lifelong learners, students, and others. The Summit had a strong focus on the future of BI and NABI.  Sessions engaged member feedback, discussed the creation of a peer-reviewed journal about broader impacts, and considered the role of the NSF CAREER Program in integrating intellectual merit and broader impacts. Slides for each presentation are available at https://broaderimpacts.net/2017-schedule/.

If you are interested in becoming a member of the National Alliance for Broader Impacts network, visit their website at https://broaderimpacts.net/join-nabi/ to join for free. Registration for the next summit, which will be held at the Providence Biltmore April 25-27, 2018 will become available on the NABI website at https://broaderimpacts.net/.

This work is partially funded by the Division of Molecular and Cellular Biosciences, Award #MCB – 1408736.

DR. SUSAN GERBI WINS THE 2017 GEORGE W. BEADLE AWARD

This is a headshot style photo of Dr. Susan Gerbi who is sitting in her laboratory in front of culture test tubes and a white board, wearing a red sweater, pink turtleneck shirt, and smiling.

MCB congratulates Dr. Susan Gerbi on her 2017 George W. Beadle Award. Each year, the Genetics Society of America honors one investigator for “outstanding contributions to the community of genetics research” such as “creating and disseminating an invaluable technique or tool, assisting the community with the adoption of a model system, working to provide a voice for the community in public or political forums, and/or maintaining active leadership roles.” This distinguished honor was presented to Dr. Gerbi during the 58th Annual Drosophila Research Conference in California.

Dr. Gerbi is the George D. Eggleston Professor of Biochemistry and Professor of Biology at Brown University. In part with NSF support, she has made many notable scientific contributions in all of the areas described above. For example, together with Dr. Joseph Gall, Dr. Gerbi created in situ hybridization, an invaluable technique to locate genes on chromosomes. Additionally, she developed a novel Replication Initiation Point Mapping (RIP) technique that enabled researchers to pinpoint the start site for DNA replication in eukaryotes. Dr. Gerbi and her group also solved the first sequence of eukaryotic 28S ribosomal RNA (28S rRNA). By comparing it to its bacterial homologue (23S rRNA), Dr. Gerbi and her team identified both regions of variability (expansion segments), which aid researchers during phylogenetic analysis, and key regions of conservation (core secondary structure and domain specific conserved sequences) that are held constant among organisms to maintain rRNA function. Further, Dr. Gerbi was the first to identify an in vivo role for U3 small nucleolar RNA, which promotes ribosomal RNA folding and processing, and she was the first to develop a fluorescence-based method to track localization of small RNAs in vivo, which allowed for the identification of specific sequences that target the RNAs to the sites of ribosome assembly in the nucleolus.

Dr. Gerbi and her research team also developed Sciara coprophilia as a model organism, mapping the fly’s genome using a new, handheld DNA sequencing technology called the Oxford Nanopore MinION. (The MinION made a recent appearance in space when it was used by NASA Astronaut Kate Rubins to sequence DNA on the International Space Station.) With the genome, transcriptome, and methodology for genome editing now available, Dr. Gerbi is actively promoting the use of Sciara as a model organism to mine its unique biological features, including a monopolar spindle in meiosis, non-disjunction, chromosome imprinting, and elimination. Studies on Sciara offer new insights into the mechanisms of locus-specific DNA re-replication, which may serve as a paradigm for gene amplification in cancer. This work was partially funded by the Genetic Mechanisms cluster of the Division of Molecular and Cellular Biosciences, Award #MCB-1607411.

Dr. Gerbi has also served the scientific community in numerous leadership positions and science advocacy roles. For example, Dr. Gerbi was Founding Chair of the Department of Molecular Biology, Cell Biology, and Biochemistry at Brown University, serving in that role for 10 years. Just a few of the many broader impacts of her work that have focused on training the next generation of scientists include 33 years of service as principal investigator (PI) or co-PI on Brown University’s National Institutes of Health (NIH) predoctoral training grant. Dr. Gerbi has also served as President of the American Society for Cell Biology (ASCB), fellow of the American Association for the Advancement of Science (AAAS), chair of the Federation of American Societies for Experimental Biology (FASEB) Consensus Conference on Graduate Education, founding member and Chair of the Association of American Medical Colleges (AAMC) Graduate Research Education and Training (GREAT) group, and a member of the National Academy of Sciences Committee’s Study on the National Needs for Biomedical Research Personnel. She was also a member of the National Academy of Sciences committee on Bridges to Independence, which led to NIH’s Pathway to Independence K99 award that provides research funding opportunities to postdoctoral researchers who are transitioning to faculty positions.

For these and other efforts, Dr. Gerbi has contributed greatly to the genetics community through her dedication to scientific research, leadership, and advocacy. Please join us in congratulating Dr. Susan Gerbi!