MCB joins the rest of the scientific community in congratulating NSF funded researcher Joachim Frank who, along with Jaques Dubochet, and Richard Henderson, was awarded the Nobel Prize in Chemistry for his role in the development of Cryo-electron microscopy (Cryo-EM).
“Cryo-electron microscopy fundamentally changed biology and biochemistry, allowing scientists to create 3-D reconstructions of the biomolecular processes that support life,” said NSF Director France Córdova. “The technology delivers an unprecedented look at life at the atomic scale, providing us with accurate models of everything from viruses to antibodies. Joachim Frank demonstrated that potential to NSF in 1984, when the agency helped him acquire a high-resolution electron microscope for 3-D reconstruction, and then continued to support his development of new applications for the technology over the following decades. Biochemistry owes Frank and this year’s other two Chemistry laureates, Richard Henderson and Jacques Dubochet, a debt for this important visualization tool.”
Dr. Engin Serpersu, Program Director and Molecular Biophysics Cluster Leader stated that “technological developments and improvements in data analysis transformed Cryo-EM from being suitable only to study global structural properties of biological complexes to providing 3D structures with atomic level resolution. These developments also allow researchers to examine proteins smaller than we ever imagined possible, including ones as small as 100 kDa. Undoubtedly, Cryo-EM is now one of the mainstay structural tools helping scientists in a broad range of biological problems and its development is well worth this honor.”
In response to popular feedback, and in the interest of our community, MCB will be following in GEO’s footsteps to eliminate deadlines for future proposals. We will release a new solicitation in mid- 2018 which will detail the procedure and funding priorities for proposals submitted with “no deadline.” Funding for the proposals submitted under the no-deadline solicitation will begin during the 2019 fiscal year.
Eliminating proposal deadlines offers three key advantages. First, no-deadlines allows PIs to be more strategic in building collaborations; second, no-deadline reduces the time crush on institutions; and third, no-deadlines enables NSF-BIO to work more collaboratively across the directorate to fund science that crosses levels of biological organization. NSF anticipates that this change will result in more complex, interdisciplinary projects that have the potential to dramatically advance biological science.
More information about the change will be released through FAQs, webinars, presentations, and this blog as it arrives. Read more in the Dear Colleague Letter (NSF 18-11).
A new NSF Dear Colleague Letter (DCL; NSF 17-031) has been posted: Request for Information on Future Needs for Advanced Cyberinfrastructure to Support Science and Engineering Research (NSF CI 2030).
From the DCL:
“NSF Directorates and Offices are jointly requesting input from the research community on science challenges and associated cyberinfrastructure needs over the next decade and beyond. Contributions to this Request for Information will be used during the coming year to inform the Foundation’s strategy and plans for advanced cyberinfrastructure investments. We invite bold, forward-looking ideas that will provide opportunities to advance the frontiers of science and engineering well into the future.”
We encourage MCB to weigh in – what do you see as the cyberinfrastructure that will be needed to advance molecular and cellular biosciences?
The DCL points to an external submission website (http://www.nsfci2030.org/). Please note that the deadline for submissions is April 5, 2017 5:00 PM ET. Questions about this effort and the submission process should be sent to Dr. William Miller, Office of Advanced Cyberinfrastructure, at this email address: email@example.com.