Funding Opportunity

French Agence Nationale de la Recherche/Physics/MCB Lead Agency Agreement at the Physics – Molecular and Cellular Biosciences Interface

The NSF Division of Molecular and Cellular Biosciences in the Directorate for Biological

Sciences and Division of Physics in the Directorate for Mathematical and Physical Sciences (NSF/MCB and NSF/PHY) recently released Dear Colleague Letter (DCL) “ANR – NSF/Physics/MCB Lead Agency Opportunity at the Physics – Molecular and Cellular Biosciences Interface” (NSF 21-120). This DCL announces the continued collaboration between the French Agence Nationale de la Recherche (ANR) and NSF to support projects that use multidisciplinary approaches to examine mechanisms underlying essential life processes at the molecular, subcellular, and cellular scales. Proposals that use physics based experimental and theoretical approaches are encouraged. 

Under the lead agency agreement, researchers can submit a single collaborative proposal that will go through a streamlined review process either at NSF or at ANR. In FY 2022 (October 2021-September 2022), NSF will serve as the lead agency for all proposals. Proposals should be submitted to: NSF 21-593 Division of Physics: Investigator Initiated Research Projects. The deadline for proposals is December 14, 2021. While proposals are submitted to NSF/PHY, they will be jointly reviewed by PHY and MCB.

Simultaneously, the French institution must submit a proposal with the identical Project Description, with any required additional information to ANR, via the ANR submission system (https://anr.fr/fr/appels/). The deadline for this is December 15, 2021.

For full details on submission guidelines, program priorities, and contact information, see the DCL: NSF 21-120.

NSF EFRI Solicitation: Engineered Living Systems Topic (Focus on Sustainable Engineering and Safe Built Environment)

The National Science Foundation (NSF) recently released a new solicitation (NSF 21-615) topic as part of its FY22 Emerging Frontiers in Research and Innovation (EFRI) Program, entitled, Engineering Living Systems (ELiS).

The Emerging Frontiers and Multidisciplinary Activities (EFMA) Office will host an informational webinar on October 15, 2021, at 2 PM EDT, to discuss the EFRI program and answer questions about the FY 2022/23 solicitation. To register for this webinar, go to this link.

The EFRI-ELiS topic will support transdisciplinary research to advance the design, modeling, fabrication, and manufacturing of engineered living systems to address societal needs as well as the associated ethical, legal, and social implications of using living systems as building blocks and components for next-generation sustainable engineering. More specifically, ELiS will seed and catalyze transformative and convergence research with the goal of creating living systems for sustainable engineering with a focus on three national/societal needs: Thread 1) a sustainable built environment, Thread 2) monitoring and surveillance for a safe built environment, and Thread 3) biomining for sustainable metal extraction and resource recovery. ELiS will also contribute to the development of the basic science and engineering knowledge needed to advance the respective missions of our Federal Partner Agencies including 1) NASA’s goals for sustainable space exploration and 2) the Defense Threat Reduction Agency (DTRA)’s goals for the development and deployment of enabling capabilities to understand the built environment, threats, and vulnerabilities.

Each proposal submitted in response to this topic of the EFRI solicitation is required to address one of the three research threads and each of the foundational research components listed below:

  • Foundational Research: 1) design and/or modeling, 2) fabrication and/or manufacturing, and 3) ethical, legal, and social implications.
  • Research Thread 1: Sustainable Built Environment
  • Research Thread 2: Monitoring and Surveillance for a Safe Built Environment
  • Research Thread 3: Biomining for Sustainable Metal Extraction and Resource Recovery

The full solicitation (21-615) can be found here. Letter of Intent will be due on November 10, 2021. Preliminary Proposal will be due on December 16, 2021. Full Proposal will be due on March 10, 2022.

NSF 21-100 DCL RENEWAL: BIO AND UKRI/BBSRC COLLABORATION AND BLOG ANNOUNCEMENT

The National Science Foundation’s Directorate for Biological Sciences (BIO) recently released Dear Colleague Letter (DCL) “UKRI/BBSRC-NSF/BIO Lead Agency Opportunity in Biological Informatics, Microbes and the Host Immune System, Quantum Biology and Synthetic Cell” (NSF 21-100). This DCL announces the continued collaboration between the UK Research and Innovation (UKRI) Biotechnology and Biological Sciences Research Council (BBSRC) and BIO on topics of strategic importance to both agencies. The topics for the coming fiscal year FY 2022 remain the same as those announced for FY 2021.

Under the lead agency agreement, researchers can submit a single collaborative proposal that will go through a streamlined review process either at NSF or at UKRI, on behalf of both NSF/BIO and UKRI/BBSRC.

Potential proposers should submit a letter of Intention to Submit (ITS) by September 22, 2021. If both agencies agree that the research topic fits the topical areas identified for FY 2022, researchers will be invited to submit a full proposal to the appropriate NSF or UKRI program.

Projects must address the priorities of both UKRI/BBSRC and participating NSF/BIO Divisions. Proposers must provide a clear rationale as to the need of the US-UK collaboration, including the unique expertise and collaboration that the team will bring to the project.

For full details on submission guidelines, program priorities, and contact information, see DCL NSF 21-100.

BLOG ANNOUCEMENT: The MCB Blog members will be going on a hiatus until mid-August. We hope to see you again in the fall!

New DCL: Tool Development for Cell Biology (Tools4Cells)

A new Dear Colleague Letter (DCL) was issued by the Directorate for Biological Sciences (BIO) on the development of new tools and methods to advance our understanding of cells. Tool Development for Cell Biology, or Tools4Cells (NSF 21-057), seeks to expand our knowledge of cells using interdisciplinary approaches that can leverage advances in other fields and apply them to cell biology. Some examples of these advances include gene-editing technologies such as CRISPR/Cas9 applied to probe gene localization, and the application of cryo-EM and x-ray free electron lasers to the study of protein structure and dynamics.

Read more about the DCL criteria and proposal submission details here.

Informational EDGE Webinar: January 15, 2021, 2:00pm ET

The following is reposted from the IOS in Focus blog:

The Division of Integrative Organismal Systems (IOS), together with the Divisions of Biological Infrastructure (DBI), Environmental Biology (DEB), and Molecular and Cellular Biosciences (MCB) in the Directorate for Biological Sciences (BIO) at the National Science Foundation (NSF) and the National Human Genome Research Institute (NHGRI) of the National Institutes of Health (NIH) will host a webinar about the Enabling Discovery through GEnomics (EDGE) program, which recently released a new solicitation, (NSF 21-546). Following a brief presentation, program directors from all of the Divisions and agencies will be available to answer questions from participants.

Through the EDGE program, the NSF and the NIH support genomic research that addresses the mechanistic basis of complex traits in diverse organisms within the context (environmental, developmental, social, and/or genomic) in which they function. The program also continues to support the development of innovative tools, technologies, resources, and infrastructure that advance biological research focused on the identification of the causal mechanisms connecting genes and phenotypes. 

Information on how to join the webinar live can be found below. The slides and transcript of the webinar will be posted here on the IOS blog as well as the EDGE program website after the live event.

All are welcome to join and ask questions!

Participant Instructions for the EDGE Program Webinar:

 When: Jan 15, 2021 02:00 PM Eastern Time (US and Canada) 
 Topic: EDGE Program Webinar
 
 Register in advance for this webinar:
 https://nsf.zoomgov.com/webinar/register/WN_G6jcpqjjRFCjcfSy0YbCxA
 
 Or an H.323/SIP room system:
     H.323: 161.199.138.10 (US West) or 161.199.136.10 (US East)
     Meeting ID: 161 766 4900
     Passcode: 468123
     SIP: 1617664900@sip.zoomgov.com  
     Passcode: 468123
 
After registering, you will receive a confirmation email containing information about joining the webinar.
 
If you require accessibility accommodations to participate in this webinar, send an email to ethiels@nsf.gov 14 days in advance of the webinar specifying the accommodations needed. 

Related NSF/BIO programs and Divisions
Neural Systems
Behavioral Systems
Developmental Systems
Plant Genome Research Program
Physiological and Structural Systems
Division of Biological Infrastructure
Division of Environmental Biology
Division of Molecular and Cellular Biosciences
  
Related NIH/NHGRI Divisions
Division of Genome Science
Division of Genomic Medicine
Division of Genomics and Society
  
Websites
Materials of the webinar will be available on the EDGE program website and the blogs of each of the Divisions in the Directorate for Biological Sciences following the webinar.

New Collaboration between NSF and the French Agence Nationale de la Recherche (ANR)

The National Science Foundation (NSF) has established an agreement on research cooperation with the French Agence Nationale de la Recherche (ANR). The Dear Colleague Letter, titled, “NSF/Physics/MCB Lead Agency Opportunity at the Physics – Molecular and Cellular Biosciences Interface” (NSF 20-120), encourages collaboration between the U.S. and French research communities.

Two NSF divisions – the Division of Molecular and Cellular Biosciences (MCB) and the Division of Physics (PHY) – are participating in this collaboration. Proposals must address the research priorities of each of the participating entities: ANR, MCB, and PHY. Proposals that use multidisciplinary approaches that emphasize quantitative, predictive and theory driven science aimed at understanding mechanisms underlying essential life processes at the molecular, subcellular and cellular scales are sought. Priority will be given to proposals that leverage unique resources and capabilities of partners in the U.S. and France.

A registration file (dossier) must be submitted by December 1, 2020. For full details on submission guidelines, program priorities, and contact information, see DCL NSF 20-120.

BIO Renews Collaboration with UKRI/BBSRC

a colorful abstract picture on a black background

The National Science Foundation’s Directorate for Biological Sciences (BIO) is renewing its collaboration with the UK Research and Innovation (UKRI) Biotechnology and Biological Sciences Research Council (BBSRC), described in Dear Colleague Letter (DCL) NSF 20-118.

Titled “UKRI/BBSRC-NSF/BIO Lead Agency Opportunity in Biological Informatics, Microbes and the Host Immune System, Quantum Biology and Synthetic Cell,” the DCL describes four new topical areas associated with the lead agency opportunity. The lead agency scheme allows for reciprocal acceptance of peer review through unsolicited mechanisms and helps reduce some of the current barriers to international collaborations.

There is a two-part application process: a letter of Intention to Submit (due October 21, 2020) will be reviewed for project eligibility. Eligible proposals will then be invited to submit to the appropriate lead agency program. Refer to the DCL for important details.

Projects must be a collaboration between at least one investigator in the US and one in the UK, must address the priorities of both UKRI/BBSRC and appropriate NSF/BIO divisions, and must address the topical areas identified in the DCL. Additionally, proposers must provide a clear rationale for the need for a US-UK collaboration, including the unique expertise and synergy that the collaborating groups will bring to the project.

For full details on submission guidelines, program priorities, and contact information, see DCL NSF 20-118. Please also see this NSF announcement about the collaboration.

Photo credit: agsandrew/Shutterstock.com

CAREER Webinar Scheduled in May

Learn more about the Faculty Early Career Development Program (CAREER) solicitation (NSF 20-525) in an upcoming webinar on May 13. The webinar will provide a briefing on the CAREER program and solicitation requirements along with a Q&A session. Read about significant changes to the solicitation in MCB’s previous blog post. Registration is required for the webinar, view details about registration here. Submit questions to careerwebinarqs@nsf.gov.

From The AD: New Funding Opportunities for Understanding the Rules of Life

Dear Colleagues,

BIO is excited to announce to the biological sciences community two new funding opportunities under the Understanding the Rules of Life (URoL) Big Idea: 1) Epigenetics and 2) Microbiome Theory and Mechanisms (MTM). The URoL Big Idea seeks to create a new paradigm at the convergence of science, engineering, and technology that will elucidate theoretical frameworks (rules) to enable prediction of the diversity of evolutionary solutions that biological systems use to support life processes seen across the planet. The National Science Foundation has recently invested $36 million in the first projects under the URoL portfolio from two separate solicitations and across more than thirty institutions.

The Epigenetics and MTM opportunities represent a collaboration across Directorates and Offices within the National Science Foundation. Specifically, Epigenetics intends to enable innovative research and promote multidisciplinary education and workforce training in the broad area of epigenetics, while MTM aims to understand and establish theory and mechanisms that govern the structure and function of microbiomes.

Integrative perspectives and research approaches from more than one research discipline are welcomed, as this is a cross-Directorate effort. The interdisciplinary scope of both programs aims to provide unique training and outreach opportunities to train the next generation of scientists in a diversity of scientific approaches and to engage society more generally.

Both programs offer two submission tracks:

  • Track 1 – for projects with a total budget of up to $500,000 and an award duration of up to 3 years, and
  • Track 2 – for projects with a total budget of up to $3,000,000 and award duration of up to 5 years.

For complete details on deadlines and submission guidelines, refer to the Epigenetics program website or contact the Epigenetics Team (epigen@nsf.gov), and the MTM program website or the MTM Team (microbiome@nsf.gov).

BIO looks forward to continuing working on this cross-Directorate venture.

Sincerely,

Image of the signature of Dr. Joanne Tornow, Assistant Director for Biological Sciences

Joanne Tornow, PhD
Assistant Director for Biological Sciences

Re-posted from Bio-Buzz

New solicitation – Semiconductor Synthetic Biology for Information Storage and Retrieval (NSF 20-518)

Funding is now available through the Semiconductor Synthetic Biology for Information Storage and Retrieval Technologies (SemiSynBio-II) solicitation (NSF 20-518) which seeks to leverage synthetic biology tools, concepts, and methodologies to advance the development of next-generation semiconductor information storage and retrieval technologies that are driven by biological principles and use biomaterials in the fabrication of storage and retrieval devices and systems.  

The goal of the SemiSynBio-II research program will be to foster high-risk/high-reward, multi-disciplinary, longer-term basic research leading to novel high-payoff solutions for the information-storage and retrieval industries based on recent progress in synthetic biology and the know-how of the semiconductor technology.

This program aims to seed and foster collaborations among the researchers in physics, chemistry, biology, materials science, computer science, and engineering disciplines to develop new cross-disciplinary projects and curricula that will model and integrate concepts, tools and methodology.

This solicitation builds from the previous SemiSynBio solicitation (NSF 17-557, no longer active) to include aspects of data retrieval. Proposals can be submitted during the submission window (due by 5 p.m. submitter’s local time): February 14, 2020 – March 16, 2020. Full program details including program priorities, submission guidelines, and contact information can be found in the full solicitation NSF 20-518.

Photo credit: SidorArt/Shutterstock.com