Rules of Life

From The AD: New Funding Opportunities for Understanding the Rules of Life

Dear Colleagues,

BIO is excited to announce to the biological sciences community two new funding opportunities under the Understanding the Rules of Life (URoL) Big Idea: 1) Epigenetics and 2) Microbiome Theory and Mechanisms (MTM). The URoL Big Idea seeks to create a new paradigm at the convergence of science, engineering, and technology that will elucidate theoretical frameworks (rules) to enable prediction of the diversity of evolutionary solutions that biological systems use to support life processes seen across the planet. The National Science Foundation has recently invested $36 million in the first projects under the URoL portfolio from two separate solicitations and across more than thirty institutions.

The Epigenetics and MTM opportunities represent a collaboration across Directorates and Offices within the National Science Foundation. Specifically, Epigenetics intends to enable innovative research and promote multidisciplinary education and workforce training in the broad area of epigenetics, while MTM aims to understand and establish theory and mechanisms that govern the structure and function of microbiomes.

Integrative perspectives and research approaches from more than one research discipline are welcomed, as this is a cross-Directorate effort. The interdisciplinary scope of both programs aims to provide unique training and outreach opportunities to train the next generation of scientists in a diversity of scientific approaches and to engage society more generally.

Both programs offer two submission tracks:

  • Track 1 – for projects with a total budget of up to $500,000 and an award duration of up to 3 years, and
  • Track 2 – for projects with a total budget of up to $3,000,000 and award duration of up to 5 years.

For complete details on deadlines and submission guidelines, refer to the Epigenetics program website or contact the Epigenetics Team (epigen@nsf.gov), and the MTM program website or the MTM Team (microbiome@nsf.gov).

BIO looks forward to continuing working on this cross-Directorate venture.

Sincerely,

Image of the signature of Dr. Joanne Tornow, Assistant Director for Biological Sciences

Joanne Tornow, PhD
Assistant Director for Biological Sciences

Re-posted from Bio-Buzz

New Funding Opportunities: Rules of Life Solicitations

a picture of a hand dripping drops of water onto a small plant with dramatic sunlight in the backgroundThe National Science Foundation recently announced two new solicitations: Understanding the Rules of Life: Epigenetics (NSF 18-600), and Understanding the Rules of Life: Building a Synthetic Cell (NSF 18-599). These NSF-wide opportunities are part of Understanding the Rules of Life: Predicting Phenotype, one of NSF’s 10  “Big Ideas” for future investment.

 

A headline banner reading "Understanding the rules of life: epigenetics" underneath of which is a cartoon of a short strand of DNA wrapped around three histones like three beads on a single string

Understanding the Rules of Life: Epigenetics (NSF 18-600) invites proposals which investigate heritable biological or chemical mechanisms that produce a phenotypic effect without alteration of the DNA sequence.  Projects must integrate education perspectives and research approaches from more than one research discipline (e.g., biology, chemistry, computer science, engineering, geology, mathematics, physics, social and behavioral sciences).

Full proposals are due February 1, 2019 and can be submitted in one of two submission tracks:

(1) award duration of up to 3 years and a total budget of $500,000 or

(2) award duration of up to 5 years and a total budget of $3,000,000.

The specifics of the program priorities and areas of emphasis, as well as additional limitations and guidelines, can be found in the full solicitation.

 

A title banner reading "understanding the rules of life: building a synthetic cell" over an image of a plant root tip with each cell glowing green due to GFP attached to the cell wall

Understanding the Rules of life: Building a Synthetic Cell: An Ideas Lab Activity (NSF 18-599) invites researchers to apply to participate in an inter-disciplinary Ideas Lab focused on facilitating innovative research projects for designing, fabricating, and validating synthetic cells that express specified phenotypes. Up to $10,000,000 of funding is available for successful project proposals resulting from the Ideas Lab.

Building a synthetic cell is a grand challenge at the interface between biological, mathematical, computer and physical sciences and engineering.  Meeting this challenge requires simultaneous careful exploration of the social and ethical dimensions of such research as well as educating today’s students to engage in the activities and technologies required to develop and use synthetic cells.

To apply to this program, researchers should:

  • submit preliminary proposals due December 28, 2018,
  • participate, if selected, in the Ideas Lab workshop to be held February 25 – March 1, 2019, and
  • if invited to do so, submit, as part of a team, a full proposal due May 13, 2019.

Full details regarding the specifics of the research ideas, proposal limitations, and the application process can be found in the full solicitation.